By connecting temperature and precipitation data of seven national standard meteorological stations which were evenly distributed in Hainan Island from 1959 to 2008 with the existing climatic regionalization of Hainan Island, we studied climate change of different climatic regions in Hainan Island in the last 50 years. And the result showed that the trend of temperature increase obviously existed in these regions in the last 50 years, with warming amplitudes being higher in Northeast, Southwest, Central Mountain, Southeast and Northwest regions, respectively. In interannual time scale, the warming amplitudes of annual average maximum temperature (Tmax), annual mean temperature (Tmean) and annual average minimum temperature (Tmin) were decreasing from Tmin to Tmax. In seasonal time scale, the annual mean temperature (Tmean) was increasing seasonally in different regions, with warming amplitudes being higher in winter, autumn, spring and summer, respectively. The seasonal warming amplitudes of geographic differences were similar to those in interannual time scale. What’s more, the abrupt change of Tmean was changeable in different climatic regions, being 1972-1974 in Southwest, 1979 in Northwest, 1987 in Northeast, 1985-1990 in Southeast, and 1990 in Central Mountain regions, respectively. And the annual average precipitations were changeable in different climatic regions which were higher in Central Mountain regions, then decreasing in the order of Southeast, Northwest, Northeast and Southwest. On the other hand, the annual precipitation anomaly and abrupt change of all climatic regions fluctuated sharply except Southwest region which got through the significance test (P<0.05). Generally, percentages of dry/wet seasonal precipitation accounted for 20% and 80% respectively in annual precipitation in different climatic regions. Light rainfall mainly occurred in dry season while heavy rainfall mainly in wet season. And the contribution rate of precipitation in dry season is the highest in Central Mountain region while in wet season it was the contrary. The precipitation levels of heavy rain and rainstorm had great influence on annual precipitation, which accounted for about 50% of total precipitation. And Southwest region was the heavy rainstorm and extremely heavy rainstorm-prone area.