As the top of ecological chain on the earth, our human society,nowadays,has already been in the process of modernization. Even though, no one could be living on the earth without a fully supply of natural materials and an entirely protection of environment. In fact,material supply and environmental protection are still the first needs for human society today. No matter how advanced a country is, the status of natural resource-environment is still the key preconditions for its survival,and any instability of the resource-environmental base caused whether by natural or by man himself could stop civilizations evolve. That is why inquiring a coordinated relationship between natural resource-environment and human society has become the principal target for the sustainable development of all nations.China,as one of the largest developing countries in the world, proves again the fact itself that the precondition and stability of the national resource-environmental base are the decisive factors for the changing pattern of spatial organization in human social activities of the country. It is well known that East China by south had acted as a central place of the national civilization for a long time, and has becoming even more important for the whole country nowadays since the implementation of the "Open Door Policy" in the late 1970s. Such a development of East China by south,according to the analysis of the man-Land Relationship Model in this paper,is proved to stand by better conditions of local resource and environment. It is, therefore, to fully understand this phenomenon of man-land relationship based upon the natural resource-environment could benefit a lot for a sustainable development of China in future.