转基因食品的安全性问题在世界范围内倍受关注,国内外尤其国外已经开展和正在开展许多的研究工作。实质等同性原则在转基因安全性评价中得到广泛应用,但存在一定的局限性。目前已经进行了转基因马铃薯、大豆、番茄、棉花、西葫芦、水稻、烟草以及芦笋的食用安全性评价,积累了一些研究经验和方法,得到一些有意义的研究结果,但也存在着一定的争论。文中将从评价的方法、原则和结果等几个方面报道和讨论转基因食品安全性评价的研究进展,并且指出评价中存在的问题,对转基因食品的安全性问题作了一个相对全面而客观的报道,并且总结了转基因食品安全性评价中应该注意的几个问题,对开展安全性评价工作有一定的参考价值。

The food safety assessment of transgenic organisms has been a world wide concerned issue.Although there are some limitations,the principle of substantial equivalence is widely applied in the assessment of novel food derived from transgenic orga nisms.Many kinds of transgenic food have been assessed,such as potato,soybean,tomato,cotton,rice,squash,tobacco,and asparagus.The methods,principles and results of food safety assessment are discussed in this paper,as well as the potential problems.The progress and problems for the safety assessment of food derived from transgenic organisms are reported in a relatively comprehensive and objective manner.