A cotton production management system for the Huang-Huai-Hai region in China has been established by applying the techniques of crop simulation model and knowledge engineering.It is composed of the cotton simulation model,GUI and data base.It can suggest the reasonable applications of nitrogen fertilizer,irrigation and plant growth regulator.The computer simulation experiments for selecting the optimal row spacing and planting density have been made by using the COTMAS.The results show that the selected optimal values are basically in conformity to the practical ones.