This paper discusses the purposes and significances of exploiting natural resources in Northwest China and emphatically analyses the exploitation state and exonomic development situation of four kinds of natural resources which have national significance. It puts forward the strategic objectives, strategic focal points and strategic countmeasures of exploiting the natural resources in this region. The aim is to quicken the exploitation of natural resources in Northwest China as early as possible, to balance the layout of national productive forces, to lay the foundation of the core position for the resorces production area in the Northwest, to bring the local superiority into play, and to promote the development of economic growth points in the West.